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RANK RANKL The RANK RANKL signaling pathway is
2019-05-15
RANK/RANKL: The RANK/RANKL signaling pathway is a critical component of both normal and malignant bone remodeling. RANK is a transmembrane signaling receptor and a member of the tumor necrosis receptor (TNF) superfamily that is found on the surface of OCL precursors [43,44]. RANK ligand (RANKL) is e
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El texto de Paz nos permite contemplar
2019-05-15
El texto de Paz nos permite contemplar el estado como una experiencia poética y una experiencia vital. Esto se debe en gran parte al énfasis que se pone en el cuerpo paricalcitol lo largo de , y más propiamente en el cuerpo que avanza en el sendero de Galta. La caminata física y la creación poética
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Early repolarization ER is characterized by elevation of the
2019-05-14
Early repolarization (ER) is characterized by elevation of the QRS-ST junction (J point) and QRS notching or slurring (J wave) in multiple leads, especially the inferior and/or left precordial leads. Although this finding has been considered to be a benign ECG manifestation, Haïssaguerre et al repor
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br Introduction Liver fibrosis cirrhosis is
2019-05-14
Introduction Liver fibrosis/cirrhosis is a global health problem that leads to morbidity and mortality. Alcohol abuse is one of the most common causes of liver fibrosis/cirrhosis in western developed countries and accounts for more than 50% of cirrhosis cases. Alcoholic liver fibrosis is characte
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br Conflict of interest br Introduction Acute kidney injury
2019-05-13
Conflict of interest Introduction Acute kidney injury in patients who are receiving anti-cancer treatments is an uncommon but serious complication. Such injury is often induced by nephrotoxic agents or urinary tract obstruction by space-occupying lesions. Among the many possible causes for ren
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It is noteworthy that even with
2019-05-13
It is noteworthy that, even with low tumor burden in these patients following CR, peak value at CR status is still a useful indicator for OS, both in the whole cohort, and more importantly, in the intermediate-risk subgroup. Slope is mainly determined by tissue vascularization and perfusion, but cap
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A type saddle back type or
2019-05-13
A type 2 (“saddle-back type”) or type 3 ST-segment elevation cannot substitute for a type 1, unless converted to type 1 with fever or sodium drug challenge. A drug challenge–induced type 1 can be used to diagnose BrS only if accompanied by 1 of the criteria specified above. Type 2 is characterized b
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For single shot techniques like the CBA a modified spiral
2019-05-13
For single-shot techniques, like the CBA, a modified spiral mapping catheter has been introduced for the identification of PVPs prior to ablation and also for monitoring purposes during the ablation process [6]. The Achieve™ Mapping Catheter (AC) is an intra-cardiac electrophysiological diagnostic c
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Concern about the effects on health of chemical exposure to
2019-05-13
Concern about the effects on health of chemical exposure to e-waste and e-waste recycling is increasing despite the paucity of solid research. Reported adverse effects include: fetal loss, prematurity, low birthweight, and congenital malformations; abnormal thyroid function and thyroid development;
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Poor knowledge among caretakers of how to
2019-05-13
Poor knowledge among caretakers of how to work with disability-related disorders could also be an issue. For example, poor knowledge of how to correctly position a child with severe cerebral palsy could lead to inadequate feeding; at worst, these efforts can cause aspiration and even death. Social a
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Vollmer and colleagues distinctive multilevel modelling has
2019-05-13
Vollmer and colleagues\' distinctive multilevel modelling has potential weaknesses that warrant further investigation. The authors imply that tremendous statistical power is derived from the availability of Demographic and Health Survey data for about 460 000 children and their households. But becau
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br Hasta donde yo s
2019-05-13
Hasta donde yo sé, ese texto, que es una carta abierta “Au journal La Réforme”, es el único en La Tribune des Peuples que aparece firmado con el nombre de Bilbao. De ello se podría deducir que el joven exiliado chileno habría tenido un papel marginal en la empresa comandada por Mickiewicz. Pero el
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br Introduction Acute myeloid leukemia AML
2019-05-13
Introduction Acute myeloid leukemia (AML) remains a hematologic malignancy with poor outcome and a high risk for relapse believed to be caused by the survival of leukemic stem cells (LSCs), which are responsible for disease repopulation following treatment [1]. This important implication of LSCs
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Second governments can play an important part in providing
2019-05-13
Second, governments can play an important part in providing incentives for industry to invest in discovering new uses for old drugs. For example, it buy PLX 4032 could consider the extension of patent protection for old drugs that have found new uses, for example, as embodied in the Hatch-Waxman Ac
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br Methods br Results br Discussion
2019-05-13
Methods Results Discussion For the first time, we report the characteristics of meridian acupoint temperatures in healthy medical college students, from which we can construct a meridian acupoint temperature map. The map vividly shows that the acupoint temperature is consistent within a nar
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