• br Experimental section br Acknowledgements

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  Experimental section Acknowledgements Introduction DJ-1 is a highly conserved, homodimeric protein that was originally cloned as an oncogene capable of transforming 10cl in ml in cooperation with activated ras[1]. DJ-1 is over-expressed in multiple tumor types and is positively correlated

• It is now well established that the cumulative exposure to

  2024-05-11

  

  It is now well established that the cumulative exposure to endogenous estrogens throughout a woman's life, mainly due to her reproductive history, has an impact on the risk of hormone-dependent breast cancer (Lambertini et al., 2016). Prolonged exposure to estrogens in the case of early age at menar

• The growth of cancer can control by

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  The growth of cancer can control by inhibiting the rate of cell proliferation or increasing the rate of selective apoptosis and effectiveness of anticancer agents varies according to genetic constitution of cancer. Hence, we investigated the anticancer activity of arginase against different kinds of

• By contrast with a plenty

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  By Amyloid Beta-Peptide (1-40) with a plenty of our understanding on arginine metabolism in animals and higher plants, very little thus far is known on the specific function of arginase that acts as a key control point for keeping arginine balance in edible mushrooms and neither for its physiologic

• Later on Wayner Burton Ingold Barclay and

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  Later on, Wayner, Burton, Ingold, Barclay, and Locke (1987) modified the method by using lipid to examine the ability of an antioxidant Celecoxib protect against lipid peroxidation generated by azo-compound. It was later improved using β-phycoerythrin (β-PE) as a fluorescent probe, and the ability

• In a human intervention study blood GSH levels

  2024-05-11

  

  In a human intervention study, blood GSH levels were evaluated over 6 wk in 18 male participants subjected to strenuous aerobic training and a dietary supplement of 1 g of WPI/kg of body mass per day. Blood GSH levels were significantly lower in those subjects who performed exercise that those who d

• Introduction Alzheimer s disease AD is

  2024-05-11

  

  Introduction Alzheimer's disease (AD) is a complex neurological disorder characterized by a progressive dementia resulting from synapse failure (Selkoe, 2002, Tanzi, 2005). The amyloid hypothesis maintains that the pivotal event in AD is the production of amyloid-β (Aβ) peptides following the prot

• The metabolism of amino acids into volatile

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  The metabolism of amino acids into volatile aldehydes involves both decarboxylation and deamination steps. The order of these reactions and the enzymes performing the catalysis differ among plants [13]. In tomato fruit the conversion of L-Phe to 2-phenylethanal is catalyzed by two enzymatic steps, i

• In conclusion our study would seem to

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  In conclusion, our study would seem to indicate that a hydrophilic microenvironment, which is suitable to accommodate highly hydrophilic molecules with steric hindrance such as aldose hemiacetals, allows the enzyme modulation by one of its most important physiopathological substrates. It is difficul

• formyl Drug resistance development often involves structural

  2024-05-10

  

  Drug resistance development often involves structurally un-related drugs and, specifically both conventional and targeted agents. IGROV-1/Pt1 formyl are characterized by resistance to cisplatin and reduced sensitivity to inhibitors of EGF-R and MEK, the up-stream activator of ERK1/2, associated with

• br Regulation of V ATPase assembly in

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  Regulation of V-ATPase assembly in response to changes in amino AR 231453 synthesis levels A central regulator of cell growth and metabolism is mTORC1 [38]. mTORC1 integrates signals from nutrient availability and growth factor receptors to control such processes as protein and lipid synthesis a

• By contrast with a plenty of our understanding on

  2024-05-10

  

  By rgd peptide with a plenty of our understanding on arginine metabolism in animals and higher plants, very little thus far is known on the specific function of arginase that acts as a key control point for keeping arginine balance in edible mushrooms and neither for its physiological role in postha

• CORT induced hippocampal damage has been implicated in depre

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  CORT-induced hippocampal damage has been implicated in depression, aging and long-term glucocorticoid therapy. Therefore, finding a drug that can protect hippocampal neurons from the adverse effects of CORT could have significant clinical benefits. In this regard, we tested the potential protective

• exportin HMGN proteins are subject to extensive

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  HMGN proteins are subject to extensive post-translational modifications which influence both their mode of binding to exportin and their functional activity. Like the other HMG protein families, HMGNs are substrates for many of the same enzymes that modify histone proteins (review in [175]). The hi

• r78 br Diabetic retinopathy Diabetic retinopathy is a severe

  2024-05-10

  

  Diabetic retinopathy Diabetic retinopathy is a severe sight-threatening complication associated with diabetes mellitus. It is one of the most common causes of preventable blindness in the world. The risk of developing microvascular diabetic complications increases in diabetic patients with an inc

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