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p as a cyclin dependent kinase inhibitor exert
2019-07-18
p21, as a cyclin-dependent kinase inhibitor, exert significant negative regulator of proliferation, and it could be transcriptional upregulated by p53 in order to impel transient Isorhamnetin arrest (Romanov et al., 2010). Using western blotting, we found that the protein expression of p21 upgrades
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Because most fusion detection methods were developed
2019-07-18
Because most fusion detection methods were developed to analyze paired-end reads (and especially Illumina data), they are not suitable for identifying fusion junction-spanning reads in single-end Ion Torrent libraries. Therefore, we developed the FusionDetect algorithm (implemented in the ChildDecod
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SRT2104 Within the cluster of North African populations
2019-07-17
Within the cluster of North African populations the Sousse population sample is somewhat different from the other six populations. One has to analyze more in depth the reasons of this isolation that has been shown by other genetic studies (Fadhlaoui-Zid et al., 2015). It seems that the particular ge
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Kumar et al studied Umbelliferone D galactopyranoside UFG be
2019-07-17
Kumar et al. studied Umbelliferone β-D-galactopyranoside (UFG) (benzopyrone), found in many plants exhibiting numerous pharmacological actions. The results of the study showed that UFG in a dose of 10, 20 or 40mgkg-1 per day, helps to prevent paw edema and arthritic score development for arthritis i
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The paper is organized as follows http
2019-07-17
The paper is organized as follows. Section 2 gives a brief presentation of the JPEG-LS algorithm and respective hardware implementation. In Section 3 the fault injection model and the simulation-based susceptibility analysis method are reviewed. Section 4 provides a discussion on the susceptibility
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The present study provides the first evidence
2019-07-16
The present study provides the first evidence that the human uroepithelial prostaglandin receptor in vitro respond directly, within 48h, to this carcinogen by promoting extensive vacuolation and DAPK expression. By using the TEM, ICC and Western blotting, we found that the arsenite-induced vacuoles
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Previous studies from our laboratory
2019-07-16
Previous studies from our laboratory in CD1 mice using the incisional postoperative pain model have shown that the incision induces significant mechanical postoperative hyperalgesia lasting between 7 and 10days, with peak effect between 4h-2days (Cabañero et al., 2009a, Cabañero et al., 2009b, Campi
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br Clinical studies br Practical
2019-07-16
Clinical studies Practical implications for young women Conclusion Research on the oncogenic mechanism of hormones has advanced dramatically in the latter years. The finding that progestogens are more powerful determinants of risk than estrogens in breast cancer has been added to advances i
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In ER group Histopathological examination followed
2019-07-16
In ER + group, Histopathological examination followed by Fluorescence in situ hybridization (FISH) had revealed the absence of HER2 receptors. Co-targeting of ER and HER2 appears to provide benefit without a significant increase in toxicity although formal trials have not been carried out [18]. Adop
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Our previous studies have shown that in
2019-07-16
Our previous studies have shown that in a preimplantation mouse embryo the proportion of inner to outer cells (i.e. precursors of ICM and TE, respectively) is regulated by a different frequency of differentiative cell divisions at the 8- and 16-cell stages. Low number of inner blastomeres generated
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Lidocaine solubility Finally the recent work to define
2019-07-16
Finally, the recent work to define the microcircuitry of the central amygdala and the role of specific cell populations in fear conditioning can stand as a useful model for advances in preclinical alcohol research. To date, the role of the amygdala in alcohol-related behaviors, and reward-related be
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From materials science it is
2019-07-16
From materials science, it is known that the differences in the annealing temperature is the main factor that mostly influences La (Takai et al., 2003, Cançado et al., 2006). In analogy, controlling the pyrolysis temperature and Rosiglitazone HCl during residues burning might be a key aspect to repr
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A wealth of studies support
2019-07-16
A wealth of studies support the key role of high NO in promoting higher blood flow and thus greater O2 delivery to working tissues in healthy Tibetans and thus partly compensate hypoxia induced low arterial O2 content [7,9,27]. We observed high eNOS mRNA, protein and enzyme activity in Ladakhi women
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Everolimus treatment showed an increase in
2019-07-16
Everolimus treatment showed an increase in the number of plaques and a reduction in plaque size, depending on concentration and treatment time (Fig. 1, Fig. 2). Everolimus-pretreated Madecassic acid where adsorbed less virus with more plaque formation in the initial phase of infection (Fig. 3). The
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A set of small molecule
2019-07-16
A set of small molecule LigI inhibitors were identified through an in silico structure-based screen, using the atomic resolution structure of LigI complexed with nicked DNA [[18], [26]]. This screen yielded inhibitors that were selective for LigI (L82), inhibited both LigI and LigIII (L67) and inhib
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